The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma
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چکیده
منابع مشابه
The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma.
BACKGROUND & AIMS Recent evidence suggests that hepatocellular carcinoma can be classified into certain molecular subtypes with distinct prognoses based on the stem/maturational status of the tumor. We investigated the transcription program deregulated in hepatocellular carcinomas with stem cell features. METHODS Gene and protein expression profiles were obtained from 238 (analyzed by microar...
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Carcinogenic process has been proposed to relay on the capacity to induce local tissue damage and proliferative repair. Liver has a great regeneration capacity and currently, most studies point towards the dominant role of hepatocytes in regeneration at all levels of liver damage. The most frequent liver cancer is hepatocellular carcinoma (HCC). Historical findings originally led to the idea th...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2014
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2013.08.024